The role of Mannose-binding lectin 2 (MBL2) gene polymorphisms in adenoid hypertrophy among young children
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منابع مشابه
Mannose-Binding Lectin Gene, MBL2, Polymorphisms Do Not Increase Susceptibility to Invasive Meningococcal Disease in a Population of Danish Children
Background. Neisseria meningitidis is the cause of meningococcal bacteremia and meningitis, and nasopharyngeal colonization with this pathogen is common. The incidence of invasive disease is highest in infants, whereas adolescents more often are carriers. Altered regulation or dysfunction of the innate immune system may predispose to invasive meningococcal disease (IMD). In this study, we inve...
متن کاملRapid communication: mapping of the Mannose-Binding Lectin 2 (MBL2) gene to pig chromosome 14.
Name of Gene Marker. MBL2, Mannose-Binding Lectin 2 (Mannose-Binding Protein, Serum; MBP1). Source and Description of Primers. Primers (set A) were designed based on human (GenBank accession number X15422) and cattle (GenBank accession number D73408) MBL2 sequences available in the GenBank database. Using porcine genomic DNA as a template in the PCR, these primers amplified an 831-bp fragment. ...
متن کاملMannose-binding lectin 2 (MBL2) gene polymorphisms do not influence frequency of infections in chronic lymphocytic leukemia patients
BACKGROUND Infectious complications represent the main cause of morbidity and mortality in chronic lymphocytic leukemia. It has been reported that polymorphisms of the mannosebinding lectin 2 (MBL2) genes are correlated with MBL protein serum levels and, consequently, are associated with the development of infectious diseases. OBJECTIVE The purpose of this study was to investigate the possibl...
متن کاملThe Role of Mannose-Binding Lectin-2 Gene Polymorphisms in Patients with Colorectal Cancer
Purpose: The mannose-binding lectin pathway of innate immunity is part of the first line of defense against microorganisms. Variations in mannose-binding lectin levels or activity are caused by single-nucleotide polymorphisms in the promoter region. Mannosebinding lectin may play a role as a phase reactant due to inflammatory processes related to cancer disease. Such inflammatory processes are ...
متن کاملRole of mannose-binding lectin (MBL2) genotyping in predicting the risk of recurrent otitis media (rOM).
Otitis media (OM) is the most common childhood disease. Almost all children experience at least one episode of otitis media with effusion (OME) or acute otitis (OMA) during childhood, and a substantial subgroup is confronted with recurrent episodes. If not treated adequately, OM may lead to temporary or permanent hearing loss. It is well known that bacteria and viruses cause OMA, and may play a...
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ژورنال
عنوان ژورنال: Egyptian Journal of Ear, Nose, Throat and Allied Sciences
سال: 2017
ISSN: 2090-0740
DOI: 10.1016/j.ejenta.2017.11.005